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This eMedTV segment describes how the medication works and also includes information on side effects, dosing guidelines, and more Read about natural remedies for erectile dysfunction (ED or impotence), including exercise, acupuncture, arginine, DHEA, ginseng, pomegranate juice, yohimbe, horny goat weed, and ginkgo biloba. Vardenafil hydrochloride (Levitra) was approved in September, 2003, and Tadalafil (Cialis) was approved in November, 2003. In the study, 69 percent of guys who reported that their penis problems persisted even after taking PDE5 inhibitors—first-line ED drugs such as Viagra, Cialis, and Levitra—were making some errors when downing the pills Viagra, Cialis and Levitra ED Drug Side Effects. I get dozens of guys asking me everyday what supplement is the best erection pills alternative to Viagra / Cialis, but something that is all-natural, available over the counter, Here’s a few of the best over the counter ed pills that work close (if not better than). 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