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Otherwise, you should simply miss the dose and take it normally as per the schedule. Which is generic version of Skelaxin 800 mg. The observational recipe is C12H15N03, which compares to an atomic weight of 221. See what others have said about Metaxalone, including the effectiveness, ease of use and side effects. Metaxalone Oral tablet drug summary. Per day seems awful dosage for me as seeing cramp/spasm occurs only once a week or so Medscape - Musculoskeletal pain-specific dosing for Skelaxin (metaxalone), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & …. 90 Tablets. It is best to take metaxalone tablets on an empty stomach or without food. Synthetically, metaxalone is 5-[(3,5-dimethylphenoxy) methyl]-2-oxazolidinone. Patients may buy Metaxalone without prescription and use it to reduce pain symptoms, in addition to physiotherapy and therapeutic massage. 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