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Medication and Therapy for Treating Bipolar Disorder in Children. In the study, one of the largest of its kind, researchers randomly assigned 153 children to receive a placebo, lithium or divalproex sodium, also known more commonly by its brand name, Depakote Detailed overview of medications used to treat childhood bipolar disorder plus their side-effects plus the important role of therapy. Com/drugs/depakote Depakote (Divalproex) is an anticonvulsant used to prevent seizures. May 06, 2018 · The treatment of bipolar disorder, or manic-depressive illness (MDI), is directly related to the phase of the episode (ie, depression or mania) and the severity of that phase. Only your healthcare provider can determine the length of valproate treatment that is right for you Oct 23, 2012 · The FDA expanded Depakote uses to include the treatment of manic episodes associated with bipolar disorder. 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